Tirzepatide

Tirzepatide (LY3298176) is a first-in-class, synthetic peptide that functions as a dual agonist of the GIP (Glucose-dependent insulinotropic polypeptide) and GLP-1 (Glucagon-like peptide-1) receptors. Often referred to as a "twincretin," it represents a major advancement in metabolic research by simultaneously targeting two primary incretin pathways in a single 39-amino-acid molecule.

Research Applications

Tirzepatide is studied for its dual-action effects on glycaemic control and energy balance. It stimulates insulin, suppresses glucagon, and delays gastric emptying to improve glucose regulation. Research highlights its potential in reducing insulin resistance, promoting weight loss, and supporting cardiorenal health, including chronic kidney disease and HFpEF.

Product Specifications

• Molecular Formula: C225 H348 N48 O68

• Purity: ≥99% (HPLC verified)

• Format: Lyophilised powder

Storage & Stability Protocols

• Lyophilised Powder: Stable at room temperature for 3 weeks; store at -20°C for up to 48 months.

• Reconstituted Solution: Store at 2–8°C, stable for 21–30 days.

• Protection: Keep vials away from light, heat and moisture. 

COA available on request

Note: This product is sold strictly for laboratory research and analytical purposes only. It is not intended for human or animal consumption or medical use.