Mots-C

MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a powerful 16-amino-acid peptide encoded within the mitochondrial genome, rather than the cell's nucleus. Often described as an "exercise mimetic," MOTS-c acts as a mitochondrial-derived hormone that regulates metabolic homeostasis, insulin sensitivity, and cellular stress responses.

Research Applications

MOTS-c is a messenger from mitochondria acting as a metabolic regulator, commonly called an "exercise mimetic." It activates the AMPK pathway, boosting glucose uptake, fatty acid oxidation, and insulin sensitivity. Researchers investigate MOTS-c for its potential to address age-related metabolic issues, obesity, and to enhance endurance and cellular energy.

Product Specifications

• Molecular Formula: C101 H152 N28 O22 S2

• Purity: ≥99% (HPLC verified)

• Format: Lyophilised powder

Storage & Stability Protocols

• Lyophilised Powder: Stable at room temperature for 3 weeks; store at -20°C for up to 48 months.

• Reconstituted Solution: Store at 2–8°C, stable for 21–30 days.

• Protection: Keep vials away from light, heat and moisture. 

COA available on request

Note: This product is sold strictly for laboratory research and analytical purposes only. It is not intended for human or animal consumption or medical use.