KPV

KPV (Lysine-Proline-Valine) is a potent, naturally occurring tripeptide that represents the C-terminal fragment of the larger Alpha-Melanocyte Stimulating Hormone (α-MSH). Unlike its parent molecule, KPV lacks the amino acid sequence required to trigger skin pigmentation, allowing researchers to study its powerful anti-inflammatory and antimicrobial properties without melanogenic side effects.

Research Applications

KPV is studied for its role in chronic inflammation, especially in the gut and skin. It works by inactivating NF-κB, which controls pro-inflammatory cytokines like TNF-α and IL-6. Researchers explore KPV’s potential to treat IBD and Ulcerative Colitis, as it can enter intestinal cells and lower mucosal inflammation. Its antimicrobial properties against Staphylococcus aureus and Candida albicans also make it valuable for studying wound healing, dermatitis, and immune responses.

Product Specifications

• Molecular Formula: C16 H30 N4 O4

• Purity: ≥99% (HPLC verified)

• Format: Lyophilised powder

Storage & Stability Protocols

• Lyophilised Powder: Stable at room temperature for 3 weeks; store at -20°C for up to 48 months.

• Reconstituted Solution: Store at 2–8°C, stable for 21–30 days.

• Protection: Keep vials away from light, heat and moisture. 

COA available on request

Note: This product is sold strictly for laboratory research and analytical purposes only. It is not intended for human or animal consumption or medical use.