IGF-1LR3

IGF-1 LR3 (Insulin-like Growth Factor-1 Long Arg3) is a synthetic, high-potency analogue of mammalian IGF-1. It is engineered with a 13-amino acid N-terminal extension and a substitution of Arginine for Glutamic Acid at position 3. these modifications significantly reduce its affinity for IGF-binding proteins (IGFBPs), resulting in a vastly extended biological half-life of approximately 20–30 hours compared to the 20-minute half-life of standard IGF-1.

Research Applications

IGF-1 LR3 is widely studied for its effects on cell growth, muscle hypertrophy, and metabolic regulation. It promotes protein synthesis by activating the AKT/mTOR pathway, and research examines its role in both muscle cell hyperplasia and glucose uptake, as well as its potential applications in metabolic disorders and regenerative medicine.

Product Specifications

• Molecular Formula: C400 H625 N111 O115 S9

• Purity: ≥99% (HPLC & MS verified)

• Format: Lyophilised powder

  
  

Storage & Stability Protocols

• Lyophilised Powder: Stable at room temperature for 3 weeks; store at -20°C for up to 48 months.

• Reconstituted Solution: Store at 2–8°C, stable for 21–30 days.

• Protection: Keep vials away from light, heat and moisture. 

COA available on request

Note: This product is sold strictly for laboratory research and analytical purposes only. It is not intended for human or animal consumption or medical use.